/Does syphilis pose special problems for people with HIV?

It can. People with HIV sometimes have unusual results on syphilis blood tests, which can make it more difficult to diagnose.

Additionally, they may have increased risk for neurosyphilis and are more likely to have treatment failure using the regular dose of antibiotics, and may need higher doses.

Therefore, it is important that people with HIV and syphilis follow up carefully with a doctor to make sure the infection has been successfully cured.

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